Noninvasive Positive Pressure Ventilation Sequential Therapy in Treatment of Switching Points in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease:Observation of Clinical Effectiveness
LIU Hui-li
WANG Yan
REN Fang-yuan
ZHAO Li
BAI Lin
Abstract：Objective To observe the effect of non-invasive positive pressure ventilation ( NIPPV) in different treat-ment methods of switching points in patients with acute exacerbation of chronic obstructive pulmonary disease ( AECOPD ) . Methods During August 2014 and June 2012, 128 patients with AECOPD undergoing NIPPV according to different methods of treatment were divided to the spontaneous breathing trial group (SBT group, n=64) and pulmonary infection control group (PIC group, n=64). The treatment situation and NIPPV correlation index of the two groups were observed and compared. Results The success rate of SBT group was 89. 06%, significantly higher than that of PIC group (60. 94%), and the differ-ence was statistically significant (P<0. 05). 4. 69% of SBT group underwent re-intubation, 28. 13% of PIC group underwent re-intubation, the intubation rates of the two groups were also statistically different (P<0. 05). The time of invasive mechani-cal ventilation in the SBT group was significantly longer than that in the PIC group, and the difference was statistically signifi-cant (P<0. 05). There was no significant difference between the two groups in ICU stay and in the incidence of ventilator as-sociated pneumonia (VAP) (P>0. 05). Conclusion SBT as a treatment method for NIPPV is helpful for AECOPD pa-tients in reducing the rate of re-intubation and the pain of the patients.
Keywords：Pulmonary diseasechronic obstructivePulmonary infection control windowSpontaneous breathing tri-alNoninvasive positive pressure ventilation sequential treatment
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 84-87 )