Clinical Application of Fractional Flow Reserve in Guidance of Interventional Therapy of Coronary Borderline Le-sions
WANG Cui-yan
WANG Li-hui
Abstract：Objective To analyze application effect of fractional flow reserve in guidance of interventional therapy of coronary borderline lesions. Methods 30 patients with coronary heart disease ( CHD) in the Affiliated Hospital of Inner Mongolian Medical University during May 2013 and September 2014 were given fractional flow reserve guidance coronary artery intervention therapy, and myocardial enzyme, cardiac color doppler ultrasonic examination results and post-operational adverse events were compared. Results For these 38 patients with CHD, surgery time was (54. 12 ± 6. 45)min, contrast agent dos-age was (195.65 ±23.14)ml, stent placement number was (1.61 ±0.65). 2 months after treatment, serum AST, LDH, CK, CK-MB, hs-cTnT concentrations were significantly lower than that before the treatment (P<0. 05);4 months after treat-ment, LVDd, LVDs of heart color doppler ultrasound examinations were significantly lower than that before treatment, and LVEF, LVFS were significantly higher than that before treatment (P<0. 05). During the 1-year follow-up, myocardial infarc-tion occurred in 2 cases (5. 26%), revascularizations in 3 cases (7. 89%), angina pectoris in 8 cases (21. 05%) with no case of cardiac death. Conclusion Application fractional flow reserve in guidance of interventional therapy of coronary borde-rline lesions may help to reduce stent placing, hospitalization expenses, myocardial injury degree and promote the heart func-tion recovery.
Keywords：Fractional flow reservemyocardialCoronary heart diseaseInterventional therapy
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 75-77 )