Analysis of the Factors Influencing Effect of Recombinant Human Interleukin-11 on Thrombocytopenia Patients
QU Ya-jing
MU Hai-yu
WANG Zhi-liang
ZANG Zhao-hui
DONG Hua-jiang
Abstract：Objective To detect the factors influencing effect of Recombinant Human Interleukin-11 on thrombocytopenia patients. Methods 157 patients were enrolled in this study. Age, gender, bone metastasis, hepatoma patients with cirrhosis, non solid tumor, radiotherapy, and chemotherapy were analyzed. Results All the patients in the group were given rhIL-11 therapy, and 46 cases were markedly effective (29. 3%), 12 cases (7. 6%) good, 24 cases (15. 3%) effective and 75 cases (47. 8%) invalid, and total efficiency rate was 52. 2% (82/157);age, hepatoma patients, malignant tumor of blood system showed significant differ-ences respectively (P<0. 05). Gender, bone metastasis, radiotherapy, chemotherapy showed no significant difference respectively (P>0. 05). Four influential factors finally entered into the model of Logistic regression:age, hepatoma patients with cirrhosis, ma-lignant tumor of blood system and radiotherapy. Conclusion The effect of Recombinant Human Interleukin-11 on thrombocytopenia patients with malignant tumor is related with age, hepatoma patients with cirrhosis and non solid tumor.
Keywords：Recombinant human erythropoietinNeoplasmThrombocytopeniaTreatment outcomeInfluential fac-tor analysis
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 85-87 )