Meta Analysis of Effect of Percutaneous Coronary Intervention or Optimal Medical Therapy in Patients with Stable Coronary Artery Disease
XIANG Jia-pei
MA Rui-song
Abstract：Objective To compare the efficacy of PCI and OMT in patients with stable coronary artery disease ( SCAD) . Methods The databases of Pubmed, CENTRAL, and CNKI were retrieved with computers for collecting random-ized controlled trials ( RCTs) about the comparison in the efficacy of PCI and OMT published during January 1990 and Decem-ber 2014. After rigorous evaluation on literature quality, the eligible data of RCTs was extracted and given a Meta-analysis u-sing RevMan5. 0 software. Results There were totally 13 RCTs included, and the results of Meta-analysis showed that be-tween PCI and OMT groups, the all-cause-death-events (RR=0. 86, 95%CI:0. 74~1. 00, P=0. 05), and the incidence of cardiac death events (RR=0. 71, 95%CI:0. 47 ~1. 06, P=0. 09), the incidence of nonfatal MI (RR=0. 93, 95%CI:0. 71~1. 22, P=0. 60), the incidence of revascularization (RR=0. 94, 95%CI:0. 71~1. 25, P=0. 68) had no significant difference, but the incidence rate of freedom of angina (RR=1. 18, 95%CI:1. 06~1. 31, P=0. 003) was higher in PCI group than that in OMT group. Conclusion In the treatment of SCAD patients, PCI can significantly improve the incidence of freedom of angina, but it is similar to OMT in the rate of all-cause-death, cardiac death, nonfatal MI, and revasculariza-tion, which shows the clinical advantages of PCI in treatment of SCAD patients.
Keywords：Coronary diseaseAngioplastyballooncoronaryDrug therapyMeta-analysis
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 73-79 )