Prediction of β-HCG Detection Combined with Ultrasonography for Pregnancy Outcome of Unknown Locations

DU Fei; HOU Su-ping; MOU Rong-ji

doi:10.3969/j.issn.1002-3429.2015.11.032

Abstract：Objective To explore the predictive value of ultrasonography combined withβ-Human chorionic gonado-tropin (β-hCG) detection for pregnancy outcome of unknown locations (PUL). Methods Clinical data of 120 pregnant women with PUL was retrospectively analyzed. The pregnant women were divided into normal intrauterine pregnancy group (normal group, n=34), intrauterine pregnancy abortion group (abortion group, n=23) and ectopic pregnancy group (n=63) according to the final outcome. The endometrial thickness, signal miss rate of luteal blood flow, levels of the ultrasound serum β-hCG, progesterone ( P) and ratio of β-hCG growth rate over 60% in the three groups were analyzed. Results The differences in incidence rates of abdominal pain and vagina bleeding, endometrial thickness, signal miss rate of luteal blood flow, levels of serum β-hCG, P and ratio of β-hCG growth rate over 60% in the three groups were statistically significant (P<0. 05). In normal group, the values of incidence rates of abdominal pain and vagina bleeding and signal miss rate of lu-teal blood flow were significantly lower, while the values of endometrial thickness, levels of serum β-hCG, P and ratio of β-hCG growth rate over 60% were significantly higher than those in abortion and ectopic pregnancy groups (P<0. 05). The val-ues of incidence rates of abdominal pain and vagina bleeding, endometrial thickness, signal miss rate of luteal blood flow, lev-els of serum β-hCG, P and ratio ofβ-hCG growth rate over 60% in abortion group were significantly lower than those in ectop-ic pregnancy group ( P<0. 05 ) . Conclusion Sonographic detection of endometrial thickness and luteal blood flow signal combined with serological detection of β-hCG level especially β-hCG growth rate may predict pregnancy outcome of pregnant women with PUL.