Clinical Distribution and Drug Resistance Analysis of Enterococcus Strains
SONG Juan
HUA Chuan
LI Yang
LI Su-li
YU Ying
Abstract：Objective To investigate the characteristics of distribution and the change in drug resistance of Entero-coccus to provide reference for clinical therapy. Methods The distribution and drug resistance of 485 strains of enterococci i-solated from various clinical specimens of the infections during 2011 and 2014 were retrospectively analyzed. Results Among the 485 strains of enterococci in the study, the top organism was enterococcus faecalis (53. 19%), the second was enterococ-cusfaecium (40. 41%). The main localities from the enterococci isolated were urinary tract (70. 31%), followed by secretion (14. 43%). Enterococci strains were resistant to multiple antibiotics, but sensitive to Vancomycin, Nitrofurantoin and Chlor-amphenicol. Compared with the drug resistance rates of enterococcusfaecalis to Penicillin, Ampicillin, Rifampicin and Nitro-furantoin in 2011, they were significantly decreased in 2014 (P<0. 05 or P<0. 01), and the drug resistance rates of entero-coccusfaecium to Tetracycline and high level of Gentamicin were significantly decreased in 2014 (P<0. 01). Conclusion The most common enterococci causing hospital infection are enterococcus faecalis and enterococcus faecium. The drug resist-ance rate of enterococcusfaecium is higher than that of enterococcus faecalis. The antibacterial agents should be reasonably ap-plied according to antimicrobial susceptibility test during clinical therapy. Furthermore, necessary steps should be taken to prevent the enterococcal infection and reduce the drug resistance.
Keywords：EnterococcusDistributionDrug resistanceAntibacterial agent
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 71-74 )