Clinical Effect of Surgical Treatment of Gastroesophageal Reflux Disease Related Hypertension
JI Feng
WANG Zhong-gao
HAN Xin-wei
LI Zhi-tong
WANG Li
CHEN Jian-hua
BAI Lin-feng
CUI Qiang
GAO Xiang
ZHANG Cheng-chao
Abstract：Objective To research the association between gastroesophageal reflux disease (GERD) and essential hypertension and the efficiency of laparoscopic Nissen fundoplication in the treatment of GERD-related hypertension. Methods We retrospectively analyzed the clinical data of 18 patients with essential hypertension undergoing laparoscopic fundoplica-tion for GERD between June 2011 and June 2012. Results 18 cases were diagnosed in compliance with GERD and hyperten-sion standard. The duration of GERD was (9. 4 ± 6. 0) years and the course of hypertension was (5. 2 ± 6. 0) years. The first symptoms were GERD symptoms in 13 cases and the complication of hypertension was found 1 to 19 years later. The first symptom was hypertension in 5 cases and the occurrence of GERD were from 0. 8 to 10 years later, indicating that the GERD was treated successfully. 1 year after the operation, the systolic blood pressure of these patients was decreased (t = 4. 095, P = 0. 001), and the diastolic blood pressure was decreased (t = 3. 014, P = 0. 001). Further more, the hypertension medi-cation was discontinued in 9 patients, the dose was reduced in 3 patients, and the medication was continued in 6 patients. The total score (Sc) decreased from 18. 50 (14. 25) preoperatively to 0 (2. 00) postoperatively (z = 3. 726, P = 0. 001). Con-clusion GERD is closely related to essential hypertension. Therefore, laparoscopic Nissen fundoplication is a safe and effec-tive way of treatment for patients with GERD-related hypertension.
Keywords：Essential hypertensionComplicationGastroesophageal refluxFundoplicationBlood pressure
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 77-79 )