The Effect of Vitamin E on Serum C-reactive Protein and Lipid levels in Patients with Gestational Diabetes Mellitus
YAN Da-jing
LI Yong
YE Sheng-quan
WANG Guo-zhu
TAI He
YANG Cheng-lin
Abstract：Objective To observe the changes of C-reactive protein and lipid levels in serum of gestational diabetes mellitus patients before and after vitamin E therapy. Methods 22 patients diagnosed with gestational diabetes mellitus were randomly divided into 2 groups: Observation group ( n=11 ) and Control group ( n=11 ) . The patients in both groups were given personalized diet plan, exercise scheme and continuous subcutaneous insulin infusion. In addition, the patients in obser-vation group took Vitamin E (30 mg/d). The concentration of CRP, lipid level in the serum of the patients in both groups were observed and compared after 2 and 4 weeks of treatment. Results After 2 weeks of treatment, the concentration of CRP, TC, TG, LDL-C was significantly reduced (P<0. 05) and the concentration of HDL-C was dramatically raised (P<0. 05) in ob-servation group. After 4 weeks of treatment, the changes were more obvious. On the other hand, in control group, the concen-tration of CRP, TC, LDL-C, HDL-C remained unchanged (P>0. 05) during the treatment. After 2 and 4 weeks of treat-ment, the above indexes of two groups were statistically different (P<0. 05) Conclusion Vitamin E can ease vascular in-flammatory reaction and reduce the concentration of lipid levels in serum of patients with GDM.
Keywords：DiabetesgestationalVitamin EC-reactive proteinLipid
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 57-59 )