Clinical Analysis of 39 Cases of Sporadic Amyotrophic Lateral Sclerosis
FANG Xiao-li
CAO Xing-yi
SONG Jin-lian
MEI Qian-qian
WU Shi-wen
Abstract：Objective To determine the clinical characteristics of sporadic amyotrophic lateral sclerosis (sALS), to improve the accuracy of diagnosis. Methods We reviewed 39 cases visiting the General Hospital of Chinese People's Armed Po-lice force during June 2009 and June 2014. Results The average morbidity age was (54. 7 ± 10. 7)years-old. They were mostly male patients and the peak of the course was at the 24th month. The risk of paroxysm was greatly increased in individuals who were factory workers and farmers and who used to be in good health. The main clinical manifestations included muscle weakness, muscle atrophy, fasciculations, slurred speech, drinking cough and cognitive dysfunction. About 12. 8% of sALS had cognitive impairment. The cervical cord was supposed to be the predilection site. Conclusion sALS is a middle-aged, male predominant disease. sALS accompanied with cognitive impairment may be related to frontotemporal dementia, Alzheimer's disease and other neurodegenerative disorders in some aspects. An detailed inquiry, a thorough physical check-up and timely clinical examination of electromyogram and discriminating diagnosis are important in diagnosis.
Keywords：Amyotrophic lateral sclerosisComplicationCognitive dysfunctionMisdiagnosis
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 88-90 )