Insulinoma Misdiagnosed as Epilepsy in a Long-term:One Case Report and Literature Review
YAN Yi-min
JI Liu-zhou
XIAO Lan
HUANG Shu-yu
ZOU Yi
WU Min
LIU Feng
GUAN Xiao-feng
Abstract：Objective To explore the clinical characteristics and differential diagnosis of insulinomas induced brain damage, reduce misdiagnoses. Methods A retrospective analysis of clinical data of 1 case of insulinoma misdiagnosed as schizophrenia was made, and the literature was reviewed. Results The patient with the main clinical expression of abnormal behavior, confusion, lethargy and mental retardation for 8 years had been diagnosised as schizophrenia before admission to our hospital, and had not been given any regular treatment. This time, the patient was admitted to our hospital for lethargy for 2 days. After admission, two tests of hypoglycemia were conducted and showed that her blood sugar was 2. 75 mmol/L, 1. 71 mmol/L and serum insulin was 24. 71,156. 36 mU/L, and the insuline/blood sugar ratio was 0. 50,5. 08, and glucose tolerance test was positive. Pancreatic enhancement of CT showed a pancreatic tumor. Brain CT showed cerebral atrophy. Di-agnosis of insulinoma and cerebral atrophy were diagnosed after revision. Transfer line surgical operation was performed to re-move tumor and pathologic examination confirmed the diagnosis. Postoperative blood glucose returned to normal, and the con-dition was improved. Conclusion Hypoglycemia induced by insulinoma can be manifested by symptoms in central nervous system damage. For such atypical clinical presentation of insulinoma, attention should be paid to prevent misdiagnosis as epi-lepsy, hysteria and other mental disorders.
Keywords：InsulinomaHypoglycemiaBrain atrophyMisdiagnosisEpilepsy
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 46-48 )