Cause and Preventive Methods of Blister Reaction and the Precaution after 308 nm Excimer Laser Treatment of Vitiligo
Lin Ting
Li Xue-mei
Liao Chun
Yang Hui-lan
Abstract：Objective To discuss the cause and preventive methods of blister reaction and its precaution after 308 nm excimer laser treatment of vitiligo. Methods Clinical data of 3152 patients were studied. This retrospective study involved the records of patients admitted to our department undergoing 308 nm excimer laser treatments during January 2005 and Febru-ary 2014. 181 adverse cases of local blister reaction and precaution methods were analyzed. Results During 308 nm excimer laser treatment, local skin blister reaction rate of the vitiligo patients in the research group was 5. 74%. In the group, blister reactions occurred on the head and face with a rate of 5. 07%, on and around the lips with a rate of 14. 01%, on the neck with a rate of 5. 80%, on the body with a rate of 2. 92%, and on the limbs with a rate of 5. 56%. After the occurrence of blister, all the patients suspended 308 nm excimer laser treatment for symptomatic treatment, and the average healing time of blisters was 7. 36 days. Conclusion With the minimal erythema, dose treatment dosage should be adjusted according to ery-thema reaction at the beginning of medication. Single overdose and direct irradiation on the patient's photosensitive skin should be avoided so as to reduce and prevent blister reaction.
Keywords：VitiligoLaser therapyBlister
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 81-83 )