Observation of Effect of Bronchoalveolar Lavage in Patients with Pulmonary Infection after Severe Traumatic Brain Injury
LI Jian
SONG Ting-ting
MA Long
ZHONG Hua
YU Xiang-you
Abstract：Objective To observe the effects and safety of bronchoalveolar lavage ( BAL) in patients with pulmonary infection after severe traumatic brain injury. Methods Patients were randomly divided into the treatment group and the con-trol group (n=39, each) using random digit table. All the patients were treated with conventional therapy, and the treatment group was treated with BAL besides conventional therapy. Results The results of blood gas analysis showed that the levels of PaO2 and PaO2/FiO2 in the treatment group were significantly higher than that of the control group (P<0. 05), while the lev-el of PaO2 was significantly lower than that of the control group ( P<0. 05 ) . Compared with the control group at the same time, the plasma IL-6 and TNF-αlevels were obviously lower than those before treatment, and the levels were decreased more significantly in the treatment group than that in the control group. Duration of ICU stay, days of antibiotic use, and days of mechanical ventilation were significantly fewer in the treatment group than that in the control group. There was no significant difference in mortality rate between the two groups (P>0. 05). There was no serious BAL related complications in the treat-ment group. Conclusion The BAL can significantly increase the oxygenation, control the pulmonary infection.
Keywords：BronchoscopeBronchoalveolar lavageTraumatic brain injuryComplicationRespiratory tract infection
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 94-98 )