Cause Analysis of Malignant Pleural Mesothelioma Misdiagnosed as Tuberculous Pleurisy
MEI Zhou-fanga
QIAN Linga
DU Yonga
SHI Jing-donga
HE Weia
LI Xiao-jingb
JIE Zhi-juna
Abstract：Objective To analyze clinical features and diagnosis of malignant pleural mesothelioma, so as to reduce misdiagnosis rate. Methods Clinical data were retrospectively analyzed from one case of malignant pleural mesothelioma in our hospital, and related literature was reviewed. Results Before admission, the patient complained of cough, chest tight-ness and chest pain for one month outside the hospital, and chest CT examination showed left pleural effusion, and the patient received anti TB diagnostic therapy for 2 weeks after examination of pleural effusion, but his symptoms gradually deteriorated, and so he was transferred to our hospital. CT ultrasound examination showed left pleural effusions. The serum neuron specific enolase was as high as 48 ng/ml. Biopsy pathology through thoracoscopy and immunohistochemical confirmed of malignant pleural mesothelioma. After chemotherapy of pemetrexed disodium combined with cisplatin, his symptoms were relieved re-markably and he was discharged from hospital, but his condition deteriorated and died 11 months after discharge. Conclusion When pleural effusion is difficult to characterize, especially with chest pain, malignant pleural mesothelioma should be sus-pected and thoracoscopy and open-chest examination have an important role in definite diagnosis.
Keywords：Pleural tumorMesotheliomaMisdiagnosisTuberculosispleural
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 45-48 )