Hypercalcemic Crisis Which Tends to Be Clinically Overlooked (A Report of 3 Cases and the Literature Review)
WANG Yue-yue
ZHU Hai-yan
BAN Yu
SONG Yang
MENG Qing-yi
Abstract：Objective To explore clinical features of hypercalcemic crisis and share the experiences of diagnosis and treatment. Methods Clinical data of three patients with hypercalcemic crisis in our department were retrospectively analyzed and relevant literature were also reviewed. Results The three patients had all relating clinical symptoms, including motor sys-tem, urinary system, nervous system, etc. They were diagnosed with hypercalcemic crisis on admission, whose serum calcium was 4. 07-6. 06 mmol/L. Combined with the laboratory results and enhanced iconography findings, one patient was diagnosed as having parathyroid adenoma, one was confirmed as having malignant tumor with metastasis in multiple organs, and the etiol-ogy of the third patient was uncertain due to the rapid disease progression. The last one was highly suspected for malignancy. The three patients with hypercalcemic crisis were given positive symptomatic treatment. One patient had an excellent progno-sis, but the other two died. Conclusion The patients of hypercalcemic crisis are always characteristic of varied clinical symp-toms including nervous system, digestive system, urinary system and so on, with lack of specificity. Relevant laboratory and imaging examinations may be helpful in early diagnosis and effective treatment, avoiding misdiagnosis and missed diagnosis, and improving the patient's survival rate.
Keywords：HypercalcemiaHyperparathyroidismprimaryOvarian tumorMissed diagnosisMisdiagnosis
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 23-27 )