Clinical Analysis of Bladder Neuroendocrine Carcinoma and Misdiagnosis of Preoperative Biopsy (a Report of 2 Cases)
WANG Jun
MEI Xing-ming
ZHANG Mao-yu
LI Yue-ming
WU Chen-lin
ZHANG Jian-gong
Abstract：Objective To investigate the clinical features of primary neuroendocrine carcinoma ( NEC) of bladder to improve the level of diagnosis and treatment. Methods Clinical and pathological data of 2 cases of primary bladder NEC were retrospectively analyzed, mainly on the cystoscopy biopsy and postoperative pathological diagnosis error causes and preventive measures were discussed. Results Two male patients had painless gross hematuria and tumors were located in the lateral wall. 's the tumor volume of Case 2 was big and broad, infringement of prostate congestion urethral mouth appeared to have dysuria and urinary retention. 2 cases of cystoscopy and biopsy were diagnosed as bladder transitional cell carcinoma and tran-surethral plasmakentic vaporization of bladder tumor respectively. Case 1 underwent electricity cut method, radical bladder full cut method (Case 2), both were confirmed as primary bladder NEC. Case 1 underwent systemic chemotherapy, and a postop-erative follow-up of 9 months did not find tumor metastasis, but follow-up was lost after ten months; Case 2 survived after 6 months of follow-up and no tumor metastasis was found. Conclusion Primary bladder NEC is a clinically rare and highly ma-lignant tumor. Improvement of preoperative biopsy specimen collection and pathologic examination recognition may help to a-void misdiagnosis.
Keywords：Urinary bladder neoplasmCarcinomaneuroendocrineMisdiagnosistransitional cellBiopsy
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 50-52 )