Epidemiological Investigation on Acute Paraquat Poisoning of an Emergency Department in Northwest China Region
LIU Shan-shou
HU Xiao-min
HUANG Yang
LI Jun-jie
YIN Wen
Abstract：Objective To explore the epidemiological characteristics of paraquat poisoning in Northwest China re-gion, thus to provide scientific basis for optimized strategy of paraquat poisoning. Methods A retrospective observational study was carried out from August 2012 to December 2013 in an emergency department in Northwest China region. Clinical da-ta of 157 paraquat poisoned patients admitted into the emergency department was recorded. The age, gender, marriage, occu-pation, poisoning season, approach, toxic dose, hospital length of stay and outcome of paraquat poisoned patients were de-scribed and compared among different groups of toxic doses. And then, we analyzed the patient's treatment success rate ac-cording to the toxic dose. Results (1) Among 157 paraquat poisoned patients, 92 cases (58. 6%) were women. The mean age was (31. 5 ± 12. 8) years. 102 cases (65. 0%) were married. 110 cases (70. 1%) were farmers or students from peasant families. The main poisoning approach was oral poisoning (96. 8%). The average dose of paraquat poisoning was 37. 5 (20~100) ml. and 91 patients (58. 0%) were saved finally. (2) Summer and fall were the main onset seasons, which accounted for 73. 2% of the total poisoned patients and the patients from. 20 to 29 years old accounted for the largest poisoning popula-tion (25. 5%). Compared with the females, males accounted for 55. 3% of paraquat poisoning among 10 to 19 years old, de-creasing with age increasing. (3)The average dose of male paraquat poisoning patients was larger than that of females among 10 to 19 years old. However, the mean dose of female patients started to outpace male patients among 20 to 29 years old, in-creasing with age. On the contrary, the latter would decline with age. The mean dose of female married patients was signifi-cantly larger than that of the married male patients (Z=5. 54, P=0. 021). (4) The survival rates were significantly different among different groups of toxic dose (χ2 =78. 31, P<0. 001). Conclusion Summer and fall were mainly the onset seasons of paraquat poisoning in Northwest China Region, which were the busiest farming season. The main poisoning approach was o-ral poisoning. The largest poisoning population was rural married women. The toxic dose of female patients gradually increased with the age. However, the toxic dose of male patients reached the maximum at the age of 20 to 29, and then showed a down-ward trend. With the improvement of the level of treatment paraquat poisoning, the prognosis has obviously been improved in the last few years.[ Abstract] Objective To explore the epidemiological characteristics of paraquat poisoning in Northwest China re-gion, thus to provide scientific basis for optimized strategy of paraquat poisoning. Methods A retrospective observational study was carried out from August 2012 to December 2013 in an emergency department in Northwest China region. Clinical da-ta of 157 paraquat poisoned patients admitted into the emergency department was recorded. The age, gender, marriage, occu-pation, poisoning season, approach, toxic dose, hospital length of stay and outcome of paraquat poisoned patients were de-scribed and compared among different groups of toxic doses. And then, we analyzed the patient's treatment success rate ac-cording to the toxic dose. Results (1) Among 157 paraquat poisoned patients, 92 cases (58. 6%) were women. The mean age was (31. 5 ± 12. 8) years. 102 cases (65. 0%) were married. 110 cases (70. 1%) were farmers or students from peasant families. The main poisoning approach was oral poisoning (96. 8%). The average dose of paraquat poisoning was 37. 5 (20~100) ml. and 91 patients (58. 0%) were saved finally. (2) Summer and fall were the main onset seasons, which accounted for 73. 2% of the total poisoned patients and the patients from. 20 to 29 years old accounted for the largest poisoning popula-tion (25. 5%). Compared with the females, males accounted for 55. 3% of paraquat poisoning among 10 to 19 years old, de-creasing with age increasing. (3)The average dose of male paraquat poisoning patients was larger than that of females among 10 to 19 years old. However, the mean dose of female patients started to outpace male patients among 20 to 29 years old, in-creasing with age. On the contrary, the latter would decline with age. The mean dose of female married patients was signifi-cantly larger than that of the married male patients (Z=5. 54, P=0. 021). (4) The survival rates were significantly different among different groups of toxic dose (χ2 =78. 31, P<0. 001). Conclusion Summer and fall were mainly the onset seasons of paraquat poisoning in Northwest China Region, which were the busiest farming season. The main poisoning approach was o-ral poisoning. The largest poisoning population was rural married women. The toxic dose of female patients gradually increased with the age. However, the toxic dose of male patients reached the maximum at the age of 20 to 29, and then showed a down-ward trend. With the improvement of the level of treatment paraquat poisoning, the prognosis has obviously been improved in the last few years.
Keywords：ParaquatPoisoningThe Northwest regionEpidemiologyData collection
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 8-11 )