Diagnosis and Treatment of Six Acetaminophen Poisoning Patients and Lessons from It
MA Fei
LI Yi
YU Xue-zhong
Abstract：Objective To improve the diagnosis and the treatment level of acetaminophen overdose. Methods Clin-ical data of six patients with acetaminophen poisoning from December 2008 to April 2014 was retrospectively analyzed. Results The major manifestations of six patients were confusion, malaise, nausea, vomiting, dizziness and headache. The laboratory examination showed obvious hepatotoxicity. All the patients were diagnosed as acetaminophen poisoning by medication history acquired from the patients or family members, blood screen and urinalysis. All patients received N-acetylcysteine treatment. Five patients were discharged with improvement. One patient gave up the therapy because of severe acute pancreatitis. Con-clusion Acetaminophen poisoning is easy to be misdiagnosed because of nonspecific features. The acetaminophen poisoning can be diagnosed based on medical history, clinical manifestations and medical examinations, and the final diagnosis can be made depending on the blood acetaminophen screen test. The emergency staff should improve the attention to acetaminophen poisoning so as to reduce the rate of liver failure.
Keywords：AcetaminophenDrug overdosePoisoningLiver injuryEmergencies
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 13-16 )