The study on synthesis of salicylic acid derivatives and their herbicidal activity
SHANG Jinhai
LIU Zhuoqun
LIU Qian
YU Yishan
FAN Runpeng
LI Pan
Abstract：Salicylic acid(SA),as a key regulator in plants,is of great significance for plant growth regula-tion.In this study,18 SA derivatives were synthesized around the hydroxyl and carboxyl groups based on the structure of SA,aiming to explore new herbicides by regulating the SA signaling pathway.In the pre-liminary screening of oilseed rape and barnyardgrass seeds at 10 Pg/L and 100 Pg/L,SA-1 and SA-8 were found to inhibit the germination rate of weed seeds in a small-cup-and-pan-dish experiment.In order to further verify the inhibitory effect of SA derivatives on root length,apple seedlings were treated with 10 Pg/L,and it was confirmed that SA-1,SA-2 and SA-8 had significant inhibitory effects on root length.The results showed that SA-1,SA-2 and SA-8 exhibited superior herbicidal activities compared with SA,and the herbicidal activities of SA-1,SA-2 and SA-8 were also tested in a scaled-up experiment,in which oilseed rape,amaranth,barnyardgrass,and marestail were sprayed at the doses of 375 g/ha,750 g/ha,and 1 500 g/ha.The results showed that SA-1,SA-2 and SA-8 exhibited superior herbicidal activities com-pared with SA.In this study,SA-1,SA-2 and SA-8 were selected as three compounds with significant in-hibitory effects on weeds by taking SA signaling pathway as the entry point,which opens up a new path for the research and development of new herbicides.
Keywords：Salicylic acidderivativeshormonesherbicidal activity
Publication Date：2026-04-25
Online Publishing Date：2026-08-28(First online date of this platform, not the publication date of the document)
Pages：10( 307-316 )