Synthesis and bioactivity of strigolactone analogues
HE Hongfei
KAI Linfeng
QIN Chao
LÜ Pei
Abstract：Strigolactones are a class of plant hormones known for promoting seed germination and regula-ting plant physiological functions.In this study,twenty strigolactone analogues were designed and synthe-sized through the esterification of substituted benzoic acids and benzoyl chlorides with 5-hydroxy-3-methyl-2(5H)-furanone.Their structures were confirmed by 1H NMR,13C NMR,and high-resolution mass spec-trometry(HR-MS).The promotion effect of the target compounds was evaluated by the root and shoot growth promotion rates of corn and sorghum,as well as the root growth promotion rate of sunflower.The results indicated that most compounds exhibited growth-promoting effects on corn,sorghum,and sun-flower seeds.Compound 3i demonstrated a significant promoting effect.3i had 43.6%(36.5%)and 44.5%(51.7%)promotion rate on root(shoot)growth in corn and sorghum seeds at a concentration of 1 mg/L,while it showed 56.3%promotion rate on sunflower root growth at 10 mg/L,higher than that of the positive control GR24.Quantitative analysis of endogenous hormone content showed that 3i regulated abscisic acid(ABA),gibberellins(GA),and cytokinins(CTK)during germination.Molecular docking indicated stable binding modes for both 3i and GR24 with the strigolactone receptor protein OsD14.This study provides foundational insights into the application of strigolactone analogs in enhancing crop seed germination.
Keywords：strigolactoneplant hormonemolecular dockinggrowth promotion rate
Publication Date：2026-02-25
Online Publishing Date：2026-08-28(First online date of this platform, not the publication date of the document)
Pages：11( 148-158 )