Fe-N-C Single-Atom Nanozymes for Colorimetric and Electrochemical Detection of H2O2
HU Lijun
LI Jiahui
ZHAI Yanling
Abstract：Nanomaterials with enzyme-like activity,namely nanozymes,have attracted extensive attention in the field of biocatalytics.Atomically dispersed Fe-N-C monoatomic catalysts,defined as Fe-N-C single-atom nanozymes,have a similar structure to some heme enzymes and can therefore mimic enzymatic activi-ty.Herein,Fe-N-C single-atom nanozymes were prepared by the silica template method,and the layered porous nanostructure accelerated the electron transfer and further improved the reaction kinetics.Due to its inherent physicochemical properties and chemical properties,Fe-N-C shows high activity of peroxidase mimics.In addition,Fe-N-C nanozyme still maintains high activity under high temperature and strong acid and base conditions,indicating that it has good stability.The hydrogen peroxide(H2O2)colorimetric sen-sor with a linear range of 0.05～100 mmol/L and detection limit of 0.039 mmol/L was prepared by using Fe-N-C nanozyme.In addition,the Fe-N-C nanozyme can also be applied to the electrochemical detection of H2O2.Therefore,the H2O2 colorimetric system based on Fe-N-C developed in this work has broad ap-plication prospects in clinical medicine and food environment analysis.
Keywords：Fe-N-Csingle-atom nanozymehydrogen peroxidecolorimetric detectionelectrochemical detection
Publication Date：2024-04-28
Online Publishing Date：2026-08-28(First online date of this platform, not the publication date of the document)
Pages：7( 62-68 )