Separation and Determination of Three Epinephrine′s Analogs by Capillary Electrophoresis
Abstract:A method based on capillary electrophoresis was developed for separation and determination of epinephrine′s analogs namely norepinephrine,phenylephrine and isoprenaline.Under the following conditions: running buffer of 100 mmol/L NaH2PO4(pH=5.2) and separated voltage of 22 kV,the analytes were well separated in 12 min.Excellent linearity was observed in the range from 0.02 to 50 μg/mL for these three analytes,and the detection limits were all 0.01 μg/mL.The recoveries of three analytes in spiked human urine were 94.85%-105.9%.
Keywords:norepinephrinephenylephrineisoprenalinecapillary electrophoresis
Publication Date:2011-01-01
Online Publishing Date:2026-08-28(First online date of this platform, not the publication date of the document)
Pages:3( 15-17 )
