Analysis of factors influencing the efficacy of treatment for unilateral sudden deafness

SONG Qiuling; WU Li

doi:10.3969/j.issn.2097-1753.2025.04.016

Abstract：Objective To investigate the factors influencing the efficacy of treatment for unilateral sudden deafness.Methods A total of 304 patients with unilateral sudden deafness admitted to the Department of Otolaryngology,Heze Municipal Hospital,from January 2022 to May 2024 were selected.The treatment efficacy rates were compared under different clinical characteristics.Multivariate logistic regression analysis was used to analyse the impact of clinical characteristics on treatment outcomes in patients with unilateral sudden deafness,and the total scores of the Symptom Checklist 90 were compared before and after treatment.Results There were statistically significant differences in treatment efficacy rates among patients with different disease durations,audiogram types,and the presence or absence of anxiety and depression(χ2=7.293,23.198,10.743,P=0.001,＜0.001,=0.001).The results of the multivariable logistic regression analysis showed that disease duration(OR=3.669,95%CI:1.322～10.177),hearing curve(OR=2.878,95%CI:0.273～30.284),and anxiety/depression(OR=2.846,95%CI:1.177～6.879)were identified as factors influencing treatment efficacy in patients with unilateral sudden sensorineural hearing loss.After 2 weeks of treatment,the total Symptom Checklist 90 score was higher than before treatment,with a statistically significant difference(t=43.504,P＜0.001).Conclusion The factors influencing the efficacy of treatment for unilateral sudden deafness are duration of illness,type of audiometric curve,and anxiety and depression.Therefore,these factors should be prioritised in clinical treatment.