Contributors to hyperuricemia in military aircrews
SANG Yuan
JING Hongjiang
LI Feng
LIU Peng
WANG Ruoyong
MU Huiling
BAI Shuang
WANG Yawen
CHEN Ximeng
LIANG Liping
DU Peng
Abstract：Objective To investigate the prevalence of hyperuricemia(HUA)in military aircrews and analyze the contributing factors so as to provide a reference for the prevention and treatment of HUA.Methods The clinical data of 1 531 military aircrews admitted to the Aviation Medicine Department of Air Force Medical Center between December 2017 and December 2020 was retrospectively analyzed,including age,gender,aircraft types,flight time,height,weight,BMI,blood pressure,medical history,and related biochemical test results.These aircrews were divided into the HUA group(n=402)and non-HUA group(n=1 129)according to the national diagnostic criteria for HUA.The data was compared between the two groups and multivariate logistic regression analysis was used to analyze the related contributors to HUA.Results The incidence rate of HUA in military aircrews was 26.26％(402/1 531).The HUA group had higher levels of BMI,SBP,DBP,serum creatinine(Scr),fasting blood glucose(FBG),TG,TC and LDL-C(Z=-6.920～-2.173,all P＜0.05),but lower HDL-C levels(Z=-3.300,P=0.001)than in the non-HUA group,with statistically significant differences.The HUA group also had a significantly higher incidence rate of combined glucose metabolism abnormalities,hypertension,and dyslipidemia(x2=5.728,12.562,23.756,all P＜0.05).Multivariate logistic regression analysis revealed that higher BMI(OR=1.089,95％CI:1.022～1.161),elevated DBP(OR=1.026,95％CI:1.009～1.044),increased TG(OR=1.345,95％CI:1.064～1.700),and elevated Scr(OR=1.029,95％CI:1.017～1.040)were risk factors for HUA while older age(OR=0.974,95％CI:0.959～0.990)served as a protective factor.Conclusion The prevalence of HUA in military aircrews reaches 26.26％in our aviation medicine department.Age,BMI,DBP,TG and Scr are closely related to the occurrence of the disease,which points to the need to develop personalized comprehensive prevention and treatment plans in order to reduce the occurrence and development of HUA in military aircrews.
Keywords：HyperuricemiaContributorMilitary aircrews
Publication Date：2025-06-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 209-213 )