Clinical characteristics and pathogen distribution of autogenous arteriovenous fistula infection in patients under blood purification
XIA Ling
LIU Lan
YANG Yan
Abstract：Objective To study the clinical characteristics and pathogen distribution of autogenous arteriovenous fistula infection in patients with dietary blood purification.Methods This trial is a prospective case study,125 patients with chronic renal failure who underwent blood purification in suining central hospital from January 2019 to May 2021 were selected as the subjects.According to clinical diagnostic criteria for autogenous arteriovenous fistula infection,12 patients in the infected group and 113 patients in the uninfected group were enrolled.The general data and risk factors of autogenous arteriovenous fistula infection were compared between the two groups,and the distribution of pathogenic bacteria in patients with autogenous arteriovenous fistula infection was analyzed.Results There were statistically significant differences in age(t=31.796,P＜0.001),diabetes mellitus(x2=15.379,P＜0.001),hypertension(x2=5.071,P＜0.001)and albumin(t=12.789,P＜0.001)between the infected and uninfected groups.Higher age(OR=2.773,95％CI:1.369～5.616),lower albumin level(OR=0.330,95％CI:0.163～0.667),diabetes(OR=2.886,95％CI:1.700～4.900),hypertension(OR=1.448,95％CI:1.100～1.905)were risk factors for autologous arteriovenous fistula infection(all P＜0.05).The pathogenic bacteria in the infected group were analyzed,and it was found that thepatients were mainly infected with gram-positive bacteria,among which Staphylococcus aureus and Staphylococcus epidermidis were the dominant bacterial groups.The results showed that the Gram-positive bacteria,Staphylococcus aureus,Staphylococcus epidermidis,Staphylococcus haemolyticus and Enterococcus faecalis in the infected group were more resistant to penicillin,amoxicillin,cefazolin,piperacillin,erythromycin,gentamicin,clindamycin and ciprofloxacin.Conclusion In the treatment of blood purification patients,Gram-positive bacteria infection was the main one,among which Staphylococcus aureus and Staphylococcus epidermidis were the dominant bacterial groups.Resistance to penicillin,amoxicillin,cefazolin,piperacillin,erythromycin,gentamicin,clindamycin,and ciprofloxacin is more obvious.
Keywords：Blood purificationAutogenous arteriovenous fistula infectionRisk factorsFlora distributionDrug resistance
Publication Date：2024-10-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 431-434 )