Efficacy of ultrasound-guided hypertonic glucose injection against chronic injury of anterior talofibular ligament

LIAO Dongchu; MAO Ji; HU Zeying; WANG Mingfeng; WU Zhibin; LI Lu; ZHU Junjie; WU Hongguang; WANG Yuqi; MAO Longfei; SUN Xiyang; WANG Yazhen

doi:10.3969/j.issn.2097-1753.2024.04.010

Abstract：Objective To observe the therapeutic effect of ultrasound-guided hypertonic glucose injection against chronic anterior talofibular ligament injury so as to provide tips for clinical conservative treatment.Methods Sixty patients with chronic pain caused by unilateral ankle sprain were randomly divided into group A and group B.Patients in group A were treated with hypertonic glucose injection while patients in group B underwent ultrashort wave combined with kinesio taping.The ultrasound manifestations of the anterior talofibular ligament and visual analogue scale(VAS)scores were evaluated before treatment and 1 month,3 and 6 months after treatment.Results VAS scores and AOFAS scores showed that there were statistically significant differences in time effect,inter-group effect and interactions(Fgroup=34.276,97.236,Ftime=369.061,322.951,Finteraction=23.759,11.175,all P＜0.001).The VAS scores of group A at 1,3 and 6 months after treatment were all improved,and the differences were statistically significant(all P＜0.001),The AOFAS scores of group A at 1,3 and 6 months after treatment were all improved,and the differences were statistically significant(all P＜0.001),The case was the same with VAS scores(all P＜0.001)and AOFAS scores(all P＜0.001)of group B.At 1,3 and 6 months after treatment,the VAS scores of group A were lower than those of group B,and the difference was statistically significant(P=0.010,＜0.001,＜0.001),while the AOFAS scores of group A were higher,and the difference was statistically significant(all P＜0.001).Conclusion For patients with chronic anterior talofibular ligament injury,ultrasound-guided hypertonic glucose injection is safe and effective,which should be made more accessible.