Effect of cabin noise on sedation in rabbits with hemorrhagic shock in air transport evacuation aircraft
JI Jun
XIN Xin
BAI Yu
LIU Jun
XU Yuhai
Abstract：Objective To observe the effect of cabin noise in an air evacuation aircraft on rabbits after resuscitation from hemorrhagic shock at different levels of sedation.Methods Twenty New Zealand rabbits had their sedation maintained with propofol,while the BIS was controlled at 80,70,and 60,respectively.The noise of an airtransport evacuation aircraft was stimulated in the sound isolation room.The changes of the BIS,MAP,HR,and SpO2 were observed before and after stimulation.Results When the BIS was 60,there were no statistically significant changes in the MAP(t=0.921,P=0.363),HR(t=0.986,P=0.363),SpO2(t=0.133,P=0.895)or pupil diameter(t=0.231,P=0.818)before and after noise stimulation in experimental rabbits.When the BIS reached 70,there were no statistically significant differences in the MAP(t=1.510,P=0.139),HR(t=0.363,P=0.719),SpO2(t=0.137,P=0.892)or pupil diameter(t=1.435,P=0.159)before and after stimulation,but there were significant changes in the BIS(t=10.221,P＜0.001).When the BIS was 80,there were no significant changes in SpO2(t=0.381,P=0.703)before and after noise stimulation,but the BIS(t=11.863,P＜0.001),MAP(t=7.946,P＜0.001),HR(t=6.288,P＜0.001),and pupil diameter(t=11.863,P＜0.001)were significantly different.Conclusion The cabin noise in the air evacuation aircraft during flight could affect the sedation of rabbits when the BIS is maintained at 80 and 70,and the hemodynamics of rabbits when BIS is maintained at 80.
Keywords：Aeromedical evacuationNoiseSedation treatment
Publication Date：2023-12-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 481-484 )