Comparison of distribution and drug resistance of acinetobacter baumanii in tertiary hospitals in different regions
LI Liang
LIU Peihui
LV Yue
DING Shan
CHEN Wenzheng
ZHU Qiushi
YAN Juan
YANG Hao
PENG Jiemin
SUN Jifen
Abstract：Objective To summarize the distribution and drug resistance of Acinetobacter baumannii in tertiary hospitals in different regions of China and to provide evidence for rational use of drugs, control of hospital infections and for the development of new drugs. Methods Infected patients hospitalized between June 2014 and June 2015 were collected before their sputum, blood and wound exudate were isolated and cultured.Drug resistance was also analyzed using the standards of CLSI and WHONET 5.6 while SPSS 20.0 software was used for statistical analysis. Results A total of 1950 strains of pathogenic bacteria were detected in the six regions, most of which were detected in central ICUs(16.63±4.36)%, departments of neurosurgery (15.97±4.28)%, departments of general surgery(14.29±2.01)% and departments of vasculocardiology (17.92±2.66)%. The samples mostly came from sputum(72.84±3.52)%, urine(7.38±1.53)% and hydrothorax/ascites(5.65±1.89)%. The resistant rate of Acinetobacter baumannii to the tested antimicrobial drugs was generally over 60 percent. Conclusion Acinetobacter baumannii mainly comes from vasculocardiology deparments and central ICUs, possibly because of the weak immunologic resistance of patients. Acinetobacter baumannii is widely resistant to antimicrobial drugs. Therefore, the best way to control Acinetobacter baumannii infections is to strengthen surveillance and to contain its spread.
Keywords：acinetobacter baumanniiantibioticsdrug resistance
Publication Date：2018-01-01
Pages：4( 48-51 )