Clinical effect of postoperative nasal bile duct drainage in treatment of postoperative pancreatitis

ZHANG Yafei; PAN Weikang; WU Ali; WU Bing; WANG Li; ZHANG Zhao

doi:10.3969/j.issn.2095-3402.2018.01.010

Abstract：Objective To investigate the clinical effect of nasobiliary drainage in the prevention of pancreatitis after endoscopic retrograde cholangiopancreatography(ERCP). Methods One hundred and eighteen patients admitted to our hospital between January 2012 and December 2016 and given successful ERCP were selected as subjects. The clinical data of all these patients was analyzed by systematic review. The patients were divided into Group A of 72 cases(nasal bile duct drainage)and Group B of 46 cases(no nasobiliary drainage)according to the implementation of nasal drainage after surgery. The general clinical data of these patients was recorded and the incidence of complications such as pancreatitis and hyperamylasemia was recorded. Related indexes of these patients and the incidence of complications were compared between the two groups. Results The levels of serum amylase and lipase in Group A were significantly lower than those in Group B, and the difference was statistically significant(P<0.05). And the serum amylase of 2 groups increased when compared with that of 2 h after operation, but the A group decreased after 24 h and the B Group continued to rise (P<0.05). The lipase in the 2 groups increased significantly after 12 h and 24 h (P<0.05) in the 2 groups. The incidence of complications, such as pancreatitis, in Group A was significantly lower than that in Group B, and the difference was of statistical significance(P<0.05). Conclusion Nasal bile duct drainage can significantly reduce the incidence of complications such as pancreatitis after treatment of ERCP, which can be used as a preferred drainage method in clinical practice.