Clinical analysis of childhood vitiligo prognosis assessment

BAI Mingming; SHI Fei; CAI Ruikang; XU Canlong; ZHANG Si

Abstract：Objective To establish a model for evalution of the correlations between the clinical characteristics and prognosis of childhood vitiligo and to use the model to predict the skin lesion prognosis of such patients with given survey information. Methods Data on skin lesions were researched and a complete medical history of each patient was established through literature search. Information on clinical characteristics of childhood vitiligo was collected. The therapeutic program was a combination of TCM and western medicine, involving Chinese herbal medicine, oral microelements and vitamins combined with PUVA photochemotherapy. Results In this research, 60 patients were admitted and no one dropped out. A total of 150 skin lesions were observed. After integrative medicine therapy, 24%of the cases (36 skin lesions) were cured, 21% (21 skin lesions) were markedly effective, 20% (30 skin lesions) were effective and 35% (52 skin lesions) were invalid. The overall effective rate was 65%. PUVA exposure time, skin lesion position, white hair around skin lesions, areas of the skin lesion and treatment specifications were considered impact factors (P<0.05) and incorporated into the regression model. Conclusion The efficacy of integrative medicine therapy is significant, the overall effeetive rate was 65%. This research shows that PUVA exposure time, skin lesion position, white hair around skin lesions, areas of the skin lesion and treatment specifications are of great significance in predicting the prognosis of childhood vitiligo.