Effect of secondary sentinel lymph node with concurrent D2 radical resection of gastric cancer on results of surgery

HE Yuan

Abstract：Objective To observe the effect of secondary sentinel lymph node with concurrent D2 radical resection of gastric cancer on the outcome of operations. Methods 78 cases of patients who had undergone D2 radical resection of gastric cancer at our hospital between June 2013 and June 2014 were selected and randomized into observation group and control group, with 39 cases in each. The control group underwent D2 radical resection of gastric cancer while the observation group underwent secondary sentinel lymph node (SSLN) with concurrent D2 radical resection of gastric cancer. After operation, the two groups were followed up for 18 months. The basic conditions of operation (operation time, intraoperative bleeding volume, the number of lymph nodes removed) and postoperative recovery (anal exhaust time, time of off-bed activities, length of hospital stay) were compared between the two groups. The incidence of postoperative complications and recurrence were observed and compared between the two groups. Follow-up was carried out to find out about the status of disease-free survival. Results The operation time of the observation group was visibly longer than that of the control group (P<0.01). However, the intraoperative bleeding volume was significantly less, and the number of lymph nodes removed was significantly larger (P<0.05). The anal exhaust time, time of off-bed activities and length of hospital stay of the observation group were visibly shorter than those of the control group (P<0.01). The recurrence rate and incidence of complications in the observation group (10.26%, 15.38%) were significantly lower than those in the control group (28.21%, 38.46%) (P<0.05). The disease-free survival rate in observation group (73.68%) was significantly higher than that in the control group (51.38%) (P<0.05). The survival rate (92.11%) was slightly higher than that in the control group (86.49% ) (P>0.05). Conclusion The application of SSLN with concurrent D2 radical resection of gastric cancer can significantly improve the operation results, promote recovery, significantly reduce the incidence of complications and recurrence rate, and boost disease-free survival. This approach is of important value in improving clinical curative effects and long-term survival.