Effect of dezocine suppressing fentanyl-induced cough during general anesthesia induction
WANG Li
GAO Yan
LIU Hui
XING Zhen
LI Fulong
GE Liping
Abstract：Objective To evaluate the suppressive effect of intravenous dezocine on fentanyl-induced cough during the induction of general anesthesia.Methods 140 patients with induction of general anesthesia at March 2013 to March 2014, American Society of Anesthesiologists physical statusⅠ~Ⅱ, were randomly divided into two groups:experimental group(n=70)and control group(n=70). Experimental group was given intravenous dezocine 0.1 mg/kg and 10 ml matching placebo at 10 min after induction of anesthesia. Control group was given 9% NaCl, 10 ml placebo 10 min after the induction of general anesthesia. The occurrence of cough was recorded 2 min after fentanyl bolus. Results 1 patient in the dezocine group had cough, and 53 patients in the control group had cough. The difference was statistically different between these two groups(P<0.05).Conclusion The results demonstrated that intravenous dezocine was more effective in suppressing fentanyl-induced cough in our patients.
Keywords：FentanylDezocineCoughPreemptive analgesia
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 243-245 )