Comparison of chloroprocaine with lidocaine in preventing propofol injecting pain
FU Runqiao
PENG Xiaofeng
REN Haiqiang
XUE Mianrong
Abstract：ObjectiveTo evaluate effects of chloroprocaine and lidocaine to prevent propofol injecting pain. MethodsOne hundred and sixty-five adult patients undergoing abortion were randomly divided into chloroprocaine (CP,n=55), lidocaine (Li,n=55) and normal saline (control group,n=55) groups. A dose of 4 ml was venous injected at 30 s before 2 mg/kg propofol anesthesia given by 2% CP, 2% Li or control group. 0.5~1 mg/kg was added when the depth of anesthesia was not enough.ResultsThe incidences of painlessness of propofol injection were higher (P<0.01)in group CP,accounting for 92.7%, 60.0% and 43.6% in group CP, Li and control respectively, and injecting pain grade was lower in group CP than Li and control. It was lesser significant (P<0.01) in group CP and Li than control group about propofol requirements and quicker significantly (P<0.05) in group CP and Li in waking up from anesthesia.Conclusions Chloroprocaine is better than lidocaine in preventing pain caused by propofol venous injection, and can synergy and strengthen propofol anesthesia, reducing propofol requirements in therapeutic abortion.
Keywords：ChloroprocaineLidocainePropofolInjecting painTherapeutic abortion
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 165-167 )