The clinic research of surgical therapy for primary hyperparathyroidism
DAI Dajiang
HUANG Rongrong
ZHANG Haihong
ZHENG Aimin
Abstract：ObjectiveTo discuss the operation mode for primary hyperparathyroidism (PHPT), and evaluate the difference of clinic symptoms and the change of serum calcium, parathyroid hormone beforeand after the surgical therapy. MethodsIn this study, 20 patients with PHPT who received surgical therapy between 2006 and 2011 were selected. Among them, 12 cases of parathyroid adenoma received adenoma resection, 8 cases of parathyroid hyperplasia received total resection(part of the relatively normal parathyroid gland were cut into 1 mm diameter size, and 15 to 25 pieces of gland were buried withinthe sternocleidomastoid). Serum calcium and parathyroid hormone were detected after the surgery and follow-up were achieved in some of the patients.ResultsSerum calcium, parathyroid hormone significantly decreased(P<0.01), and serum calcium returned to normal in 1~8 d after surgery. Among the 10 follow-up patients, symptoms of urinary calculi, pathological fractures and bone defects were significantly improved.ConclusionSurgical therapy can obviously improve clinical symptoms and quality of life in patients with PHPT.
Keywords：Primary hyperparathyroidismSerum calciumParathyroid hormone
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 92-93 )