The study on predicting hypertensive disorders in pregnancy by noninvasive hemorrhage dynamics at the 12th gastation week

WANG Bin

Abstract：Objective To explore the feasibility about predict the hypertensive diseases at the 12th gestation week by the measurement of noninvasive hemorrhage dynamic. Method 472 cases of pregnant women adhered to no secondary disorders and no complications were recruited randomly. They were divided into two groups: the observation group (233 cases)and the control group(239 cases). The observation group cases were measured at their 12th gestation week with the method of noninvasive hemorrhage dynamics, and the area of mean pulse graph2 (AMP2) ≥90% or the central artery pressure(CASP)≥100 mmHg was designed as the positive predict norm; the control group cases were tested at their 20th gestation week with the method of mean artery pressure, whose ≥85 mmHg was appointed as the positive standard. Result In the observation group, the area of mean pulse graph2 (AMP2) ranged from 71.30% to 134.51%,the average 87.91%±20.93%, the medium 85.90%, the central artery systolic pressure(CASP) arrayed from 81.22 mmHg to 115.43 mmHg, the average (83.76±22.59) mmHg, the median 83.21 mmHg, the predict patient number 14, the predict morbidity 6.01 %, the actual patient number 12, the actual morbidity 5.15%, the sensitiveness 85.71%, the specificity 99.10%. In the control group, the mean artery pressure (MAP) ranged from 69.33 mmHg to 106.15 mmHg,the average(81.33±18.47)mmHg, the median 80.27 mmHg, the predict patient number 41, the predict morbidity 17.67%, the actual patient number 13, the actual morbidity 5.60%, the sensitiveness 31.70%, the specificity 88.66%. The differences in the sensitiveness and the specificity between the two groups relatively were very significant(P<0.05). Conclusion The method noninvasive hemorrhage dynamics adopted AMP2≥90% or CASP≥100 mmHg measured at 12th gestation week as positive predict standard is feasible for the superiority of earlier predicting, higher sensitiveness, keener specificity, etc.