Correlated research of detection for serum vancomycin concentrations between high performance liquid chromatography and fluorescence polarization immunoassay
HUANGJin
SONGQing
ZHANGHua-feng
XIAOJian
YEYang-min
Abstract：Objective The consistency of the results of serum vancomycin concentration the high-performance liquid chromatography (HPLC) and fluorescence polarization immunoassay (FPIA) were studied.Methods Serum vancomycin concentrations for 30 patients were measured by HPLC and FPIA. Correlation of results were analysised.Results Means for HPLC and standard deviation (SD) were (30.04±14.02)μg/ml. For FPIA,(29.67±13.96)μg/ml.The difference between the two methods’means were (0.37±1.46)μg/ml.The correlation coefficient of the two methods was 0.9905. Conclusion Measured serum vancomycin concentration results were consistent with each other.
Keywords：High performance liquid chromatographyFluorescence polarization immunoassayVancomycinSerum drug concentration
Publication Date：2013-10-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 209-211 )