Study on clinical therapeutic effects of lower respiratory tract nosocomical infections caused by MRSA
HE Xiao-feng
CAO Jin-gui
ZHAN Hu
LIU Fang
CUI Xia
WU Di
MA Wen-jie
Abstract： Objective We aimed to investigate the therapeutic effect of antimicrobial agents for lower respiratory tract nosocomical infections caused by Methicillin-resistant Staphylococcus aureus(MRSA),and compare the clinical effects between vancomycin and teicoplanin.Methods All 64 cases of lower respiratory tract nosocomical infections caused by MRSA who were treated in our hospital were analyzed retrospectively. The differences of the clinical effects of 34 cases with vancomycin therapy and 30 cases with teicoplanin were compared. Results The effective rate of all 64 cases treated with vancomycin,teicoplanin and linezolid was 70.3%. The length of stay,effective rate and MRSA clearance rate between vancomycin group and teicoplanin group had no statistically significance, with 11.1 days ,65.6% and 61.8% in the former,12.1 days, 76.7% and 70.0% in the latter.Conclusions Vancomycin, teicoplanin and linezolid could be used to treat lower respiratory tract infection caused by MRSA.Both vancomycin and teicoplanin exhibited a similar clinical efficacy.
Keywords：ResistantStaphylococcus aureusVancomycinTeicoplanin
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 105-106,113 )