Study on Optimization of Extraction Technology of Metaplexis japonic Total Flavonoids by Response Surface Methodology and Its Antioxidant Activity
LI Weijing
ZHAO Haosen
XU Wei
Abstract：Objective To optimize the extraction process of total flavonoids extracted from Metaplexis japonic and study its antioxidant properties,providing a reference for improving its resource utilization.Methods Ultrasonic extraction method was used to extract total flavonoids from Metaplexis japonic.Through a single factor experimental design,the important factors affecting the extraction rate of total flavonoids from Metaplexis japonic,including ethanol volume fraction,solid-liquid ratio,time and ultrasonic power were evaluated.The Box Behnken center combination design was used to optimize the optimal parameter levels of the four significant influencing factors.Results The optimal extraction process for total flavonoids from Metaplexis japonic was 70.00％ethanol volume fraction,a solid-liquid ratio of 1∶15,time of 30 minutes and ultrasonic power of 195 W.Under these conditions,the extraction rate of total flavonoids from Metaplexis japonic was 10.78％.The antioxidant activity experiment showed that the highest scavenging rates of total flavonoids from Metaplexis japonic on DPPH and ABTS·+free radicals were 79.28％and 88.62％,respectively.Conclusion The optimized extraction process of total flavonoids from Metaplexis japonic is feasible;the antioxidant activity experiment proves that it has good antioxidant activity.
Keywords：Metaplexis japonicflavonoidsresponse surface methodologyantioxidant
Publication Date：2025-12-30
Online Publishing Date：2026-04-02(First online date of this platform, not the publication date of the document)
Pages：8( 96-103 )