Effect of Risperidone Combined with Aerobic Endurance Training on Cognitive Function,Psychological Status,and Sleep Quality in Patients with Schizophrenia Sleep Disorders

ZHOU Zhenhua; WANG Jian

doi:10.3969/j.issn.2096-305X.2025.04.016

Abstract：Objective To explore the effects of risperidone combined with aerobic endurance training on cognitive function,psychological status,and sleep quality in patients with schizophrenia sleep disorders.Methods A total of 102 research subjects were patients with schizophrenia accompanied by sleep disorders who were hospitalized and diagnosed in Luoyang NO.5 People's Hospital from March 2022 to March 2024.They were divided into the observation group(n=51)and the control group(n=51)by the random number table method.The control group was treated with risperidone,and the observation group received aerobic endurance training on the basis of the control group.The intervention lasted for 4 weeks.The brief psychiatric rating scale(BPRS)was used to evaluate mental symptoms in the past week,the Wisconsin card sorting test(WCST)was used to evaluate cognitive function,the self-rating anxiety scale(SAS)and self-rating depression scale(SDS)were used to evaluate mental state in the past week,and the Pittsburgh sleep quality index(PSQI)was used to evaluate sleep quality.Results After 4 weeks of intervention,significant reductions were observed in all factor scores and the BPRS total score for both groups(P＜0.05),with the observation group demonstrating significantly lower scores than the control group(P＜0.05).Concurrently,cognitive performance improved:both groups showed significant increases in the number of categories completed and correct responses,alongside significant decreases in errors and perseverative errors(P＜0.05),with the observation group outperforming the control group on all these measures(P＜0.05).Furthermore,significant reductions were also seen in SAS,SDS,and PSQI scores for both groups(P＜0.05),again with significantly lower scores in the observation group compared to the control group(P＜0.05).Conclusion For patients with schizophrenia accompanied by sleep disorders,risperidone combined with aerobic endurance training has significant effects in alleviating clinical symptoms,reducing cognitive impairment,combating anxiety and depression,and improving sleep quality,and has clinical application value.