Analysis of the Imaging Characteristics and Risk Factors for Brucellar Spondylitis
WU Jinyu
YUAN Hongxia
Abstract：Objective To explore the imaging characteristics and potential risk factors of Brucellar spondylitis.Methods Inpatients with brucellosis in Liaoyang Infectious Disease Hospital from January 2020 to May 2023 were selected and divided into spondylitis group(study group)and non-spondylitis group(control group).The imaging characteristics of brucellosis spondylitis were analyzed.Univariate analysis was used to compare the differences in baseline indicators,clinical characteristics and laboratory test results between the two groups.The corresponding indicators were screened out and the potential risk factors of brucella spondylitis were analyzed by multivariate logistic regression analysis.Results(1)The main CT imaging changes of Brucella spondylitis are vertebral bone destruction,involved intervertebral disc stenosis,bone periosteal hyperplasia,sclerosis and paravertebral abscess at the edge of the vertebral body;the main imaging findings of MRI included diffuse hyperemia and edema of the vertebral body,worm erosion of the adjacent vertebral body,bone hyperplasia at the edge of the vertebral body,and narrowing of the intervertebral space.The lumbar spine is the most common site of involvement.L3-L4,L4-L5 and L5-S1 intervertebral discs are the most common areas of intervertebral disc involvement in patients with Brucella spondylitis.(2)Compared with the control group,there were significant differences in age,smoking,diabetes,lymphadenopathy,arthritis,pneumonia,pleurisy,PDW,CRP,ALP,ALB and LDL-C between the study group and the non-spondylitis group(P＜0.05).(3)Multivariate logistic regression analysis revealed that smoking(OR=2.168,P=O.004),arthritis(OR=2.678,P=0.000),pleurisy(OR=5.582,P=0.015),and elevated levels of low-density lipoprotein cholesterol(LDL-C)(OR=1.503,P=0.025)were significantly associated with the occurrence of the disease and are independent risk factors for the development of brucellar spondylitis.Conclusion(1)The imaging features of Brucella spondylitis include vertebral bone destruction,intervertebral disc stenosis,perivertebral osteoperiosteal hyperplasia,sclerosis and paravertebral abscess.(2)Smoking,arthritis,pleurisy and LDL-C are independent risk factors for Brucella spondylitis.
Keywords：brucellar spondylitisimaging featuresrisk factors
Publication Date：2025-08-30
Online Publishing Date：2025-10-17(First online date of this platform, not the publication date of the document)
Pages：7( 68-74 )