Comparison of Transurethral Resection and 2 μm Laser Resectionin the Treatment of Superficial Bladder Cancer

LIU Wenzheng; LING Feng; SHAN Jiang

Abstract：Objective To compare the efficacy and safety of transurethral plasmakinetic resection of the prostate (PKRP) and 2 μm holmium laser resection of the prostate (HOLRP) in the treatment of superficial bladder cancer.Methods From January 2012 to January 2015,62 cases of superficial bladder cancer patients in our hospital were chosen as the research subjects.According to the admission order,they were randomly divided into two groups,each with 31 cases.Group A underwent PKRP treatment,while group B received 2 μm HOLRP treatment.The therapeutic effect of the two groups were observed and compared.Results Compared with group A,group B experienced significantly less blood loss,shorter operative time,and the difference was statistically significant (P<0.05),but with no significant difference (P>0.05) in postoperative catheter indwelling time and hospitalization time.After treatment,the serum levels of IL-6,IL-10 and TNF-α increased in both groups,but compared with group A,the levels of IL-6 and TNF-α in group B were significantly lower,while IL-10 was significantly higher,with statistically significant difference(P<0.05).During treatment and follow-up period,compared with group A,the incidence of complications and recurrence rate in group B was significantly reduced,with statistically significant difference(P<0.05).Conclusion For patients with superficial bladder cancer,2 μm HOLRP proves to be effective,with fewer complications,and reduced level of body inflammation,so it is of high clinical application value.