The Application of The Small Field-of-View Biexponential Model of Multi B-Value Diffusion Weighted Imaging in Differentiating Benign of Thyroid Nodules from Malignant
LIU Yao
LI Weixiong
Abstract：Objective To assess the diagnostic value of small field-of-view biexponential model of multi b-value diffusion weigh-ted imaging in differentiating benign and malignant thyroid nodules. Methods 85 thyroid nodules from 52 patients underwent multi b-value DWI. Thyroid nodules were divided into malignant and benign groups based on the pathological findings. Compare Slow ADC, Fast ADC, f values of both groups to see whether there are statistical differences. Results The Slow ADC, Fast ADC, f values in benign group were (1. 588±0. 407) ×10-3mm2/s, (153. 548±99. 111) ×10-3mm2/s, (20. 984±8. 568)%. The Slow ADC, Fast ADC, f values in malignant group were (0. 959±0. 228) ×10-3mm2/s, (171. 392±104. 186) ×10-3mm2/s, (22. 620±8. 491)%. There were statistically significant differences of the Standard ADC and Slow ADC between two groups. There was no statistically signif-icant difference of the Fast ADC and f values in both groups. The area under the ROC curve for Slow ADC was 0. 930. Sensitivity and specificity were 90. 00% and 95. 38%. Conclusion Small field-of-view biexponential model of multi b-value diffusion weighted im-aging has diagnostic value for differentiating benign and malignant of thyroid nodules.
Keywords：thyroid nodulesdiffusion-weighted imagingintravoxel incoherent motion
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 33-35 )