Clinical Effect of Hyperoxia Solution for External Use in the Treatment of Chronic Skin Ulcers

YAN Guobiao

Abstract：Objective To investigate the clinical effect of hyperoxia solution for external use in the treatment of chronic skin ul-cers. Methods 86 cases of patients with chronic skin ulcers admitted into our hospital from January 2014 to January 2015 were select-ed and randomly divided into the observation group and the control group, with 43 cases in each group. The control group received conventional treatment, such as debridement, dressing and bandaging. The observation group was additionally given hyperoxia solution for external use. After four weeks’ treatment, the volume of surface exudates, color of the wound, granuloma, growth of epithelial tis-sue, total effective rate and wound bacterial culture detection rate of the two groups were compared (P<0. 05). Results The obser-vation group boasted of less volume of surface exudates, lower growth of granuloma and epithelial tissue and lighter color of the wound than the control group, with statistically significance difference ( P<0. 05 ) . There was no statistically significant difference in the wound bacterial culture detection rate before treatment of the two groups (P>0. 05). After treatment, the wound bacterial culture de-tection rate of the observation group (4. 7%) was less than that of the control group (20. 9%), with statistically significant difference (P<0. 05). The total effective rate of the observation group (90. 7%) was higher than that of the control group (58. 1%), with sta-tistically significant difference (P<0. 05). Conclusion Hyperoxia solution for external use proves to be with good clinical effect in the treatment of chronic skin ulcers by accelerating wound healing, which is worthy of clinical application.