Contrastive Analysis of Four Equations Based on Creatinine or Cystatin C to Evaluate Glomerular Filtration Rate
CHENG Chuangye
YANG Yanlang
ZHANG Daoyou
Abstract：Objective To adopt the common four equations based on serum creatinine or cystatin C, and compare the correlation between GFR through the calculation of the equation and rGFR measured by 99m Tc-DTPA to evaluate the applicability of the equation in chronic kidney disease and to further compare the application value of various equations in different causes of chronic kidney disease. Methods 346 first hospitalization patients with CKD through 99m Tc-DTPA renal dynamic imaging were selected from department of nephrology of Yiji Hospital from January 2011 to October 2014, the GFR value calculated by simplified MDRD equation and Cystatin C equation 2~4 and the GFR ( rGFR) measured by 99m Tc-DTPA were compared and analyzed statistically. Results All eGFR and rG-FR calculated by equations were highly correlated (P<0. 001), which had a higher value for staging diagnosis of patients with chronic kidney disease (CKD). Accuracy and precision of equation 3 were higher than those of others, GFR3 >GFR2 >GFR1 >GFR4. Con-clusion The precision of Cystatin C equation 3 is superior to the previous GFR evaluation ones, and has better applicability in differ-ent stages of CKD patients.
Keywords：chronic kidney diseaseglomerular filtration ratescystatin Cevaluation equation
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 11-14,20 )