The Content Change of PGI, PGⅡ and G-17 in Patients with Cirrhosis Serum and its Clinical Significance
ZHOU Xiaolei
WU Chunxiao
LI Ciying
Abstract：Objective To explore the content change of pepsinogenI ( PGI) , pepsinogenⅡ ( PGⅡ) and gastric secrete ele-ment-17 (G-17) in patients with cirrhosis serum and its clinical significance. Methods 97 cases of patients with liver cirrhosis in our hospital from July 2013 to November 2014 were selected as the observation group and 92 cases of patients with liver cirrhosis but with no gastrosis at the same period were selected as the control group. The serum content of in PGI, PGⅡand G-17 were detected by ELISA. Results Compared with the control group, the PGI, PGⅡand G-17 serum levels in the observation group were signifi-cantly high and the difference was statistically significant (P<0. 05). In addition, compared with the Child-Paugh a-class, the con-tent of PGI, PGⅡand G-17 in Child-Paugh c-class patients′ serum significantly increased, and the levels of PGIand G-17 in Child-Paugh B patients' serum increased significantly, with statistically significant difference (P<0. 05). Conclusion The PGI, PGⅡ and G-17 in patients with cirrhosis serum can be used as an index to characterize the stomach disease, and the content of the three indicators proves to be related with the Child-Paugh grading.
Keywords：liver cirrhosispepsinogengastric secrete element-17the child-paugh classification
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 29-31 )