Quantitative Determination of Three Active Constituents
HU Yingjie
Abstract：Objective To determine the content of ephedrine hydrochloride, pseudoephedrine hydrochloride and bitter apricot seed in Xiao'er Feire Kechuan Oral Solution by high performance liquid chromatography.Methods ARP-HPLC method was estab-lished, with emethanol-acetonitrile-water (v ∶v ∶v=9 ∶9 ∶82, adding 1% triethylamine) used as the mobile phase, and 210 nm was the detecting wave length.Results The method has higher precision and repeatability.The recovery rate of Ephedrine Hydrochlo-ride was 99.42%, RSD (%) =0.38, the rate recovery of pseudoephedrine Hydrochloride was 99.23%, RSD (%) =0.35, and the recovery rate of Bitter Apricot Seed was 99.32%, RSD (%) =0.43.Conclusion With the advantages of simplicity, sensitive-ness and accuracy, the method can be used to determine the content of ephedrine hydrochloride, pseudoephedrine hydrochloride and bitter apricot seed.
Keywords：high performance liquid chromatographyephedrine hydrochloridepseudoephedrine hydrochloridebitter apricot seedcontent
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 16-18 )