Preliminary Study on Mechanism of Hypoglycemic Effect of Syringa Veutina Kom Leaves Extract
WU Zhuo
GUO Weiying
ZHENG Rong
Abstract：Objective To explore the hypoglycemic effect of Syringa veutina Kom leaves extract in the treatment of rats with Streptozotocin-induced type 1 diabetes mellitus.Methods Rat model of type 1 diabetes mellitus was established by STZ induction. Biochemistry, radioimmunity analysis, histology and immunohistochemical method were used to observe the hypoglycemic effect of a-queous total flavonoids extracts of Syringa veutina Kom leaves and total cyclic ether aqueous extracts on diabetic rats.Results Aque-ous extracts of Syringa veutina Kom leaves were able to significantly reduce fasting blood glucose of diabetic rats and increase serum in-sulin concentration.Total flavonoids and total cyclic olefin extract can promote insulin secretion and inhibit glucagon secretion.Con-clusion Syringa veutina Kom leaves extract has hypoglycemic effect on diabetic rats.
Keywords：Syringa veutina Komextractdiabetesrats
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 4-6,15 )