The Efficacy of Mannatide Combined with Cisplatin Intracavitary in the Adjuvant Treatment of 130 Cases of Adenocarcinoma Ascites
DENG Xiaolan
Abstract：Objective To explore the clinical efficacy of mannatide combined with cisplatin intracavitary in the adjuvant treatment of adenocarcinoma ascites. Methods 130 cases of adenocarcinoma ascites patients were selected in our hospital from May 2012 to May 2014 as the research subjects and were divided into two groups. The patients in the control group (n=63) were only treated with cisplatin intravesical infusion;while the patients in the observation group (n=67) were treated with extra mannatide. Situations such as efficacy and side effects of the two methods were compared. Results The clinical total effective rate of the observation group was 95. 52%, significantly higher than that of the control group, which was 80. 95%. The difference was statistically significant ( P<0. 05), the adverse reaction rate of the observation group was 16. 42%, while that of the control group was 15. 87%, with no signifi-cant difference between the two groups (P>0. 05). Conclusions The efficacy of mannatide combined with cisplatin intracavitary in the adjuvant treatment of cancer ascites is good and safe, which should be introduced in clinical practice.
Keywords：cisplatinadenocarcinoma ascitesintravesical instillationefficacyadverse reactions
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 29-30 )