The Observation of the Effect of Antibiotic Treatment Based on Neonatal Infection Susceptibility Test Results

LIU Delang

Abstract：Objective To analyze the type of neonatal infection pathogens and their sensitivity to antibiotics, and observe the treatment effect of antibiotics based on the results of antibiotic selection. Methods 235 specimens of 100 neonatal patients with infec-tious diseases were cultured;and drug susceptibility testing was conducted to the 111 bacteria by using the modified KB method. Re-sults There were 111 submitted samples totally, including 47 Gram-positive bacteria and 64 Gram-negative bacteria. Within the 111 bacteria, there were 26 Staphylococcus aureus, 17 Klebsiella pneumoniae, 32 Escherichia strains, 10 Enterobacter cloacae, 12 Entero-coccus faecalis and 14 others;Escherichia coli and Klebsiella are common in newborn infants with bacterial pneumonia, staph infection is common in Septicemia, Escherichia coli is common in Omphalitis, and Staphylococcus aureus is common in impetigo, Gram-positive bacteria are sensitive to ciprofloxacin, cefuroxime, imipenem and cefazolin, while gram-negative bacteria are sensitive to ceftazidime, ciprofloxacin, imipenem and amikacin;A variety of bacteria are resistant to penicillin and ampicillin. Conclusion The recent com-mon neonatal infectious diseases are pathogen Staphylococcus, Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae and En-terococcus faecalis, and the most effective antibiotics are ciprofloxacin, the Thai energy and Ami Card Star.