Meta-analysis of risk factors for perioperative delirium in patients with type B aortic dissection
YU Jintian
SUN Ruixiang
JIANG Haijiao
Abstract：Objective:To systematically evaluate the risk factors for delirium in patients with type B aortic dissection during the postoperative period.Methods:Computer searches were conducted in PubMed,Web of Science,the Cochrane Library,China National Knowledge Infrastructure(CNKI),Wanfang Database,VIP Database,and Chinese Biomedical Literature Database to collect case-control studies and cohort studies on the risk factors of perioperative delirium in patients with type B aortic dissection.The retrieval time limit is from the establishment of the database to January 31,2025.Two researchers independently screened the literature,extracted the data and evaluated the risk of bias of the included studies.Then,Meta-analysis was conducted using RevMan 5.3 software.Results:A total of 6 papers were included,involving 2,063 patients.Meta-analysis showed that age[MD=5.91,95％CI(0.56,11.25),P=0.03],age≥60 years[OR=1.74,95％CI(1.20,2.53),P=0.003],and history of alcohol consumption[OR=1.50,95％CI(1.10,2.05)],P=0.01],albumin level＜30 g/L[OR=2.64,95％CI(1.06,6.59),P=0.04],erythrocyte sedimentation rate[MD=11.76,95％CI(9.20,14.32),P＜0.001],anesthesia time[MD=11.15,95％CI(8.41,13.90),P＜0.001],operation time[MD=12.16,95％CI(9.07,15.25),P＜0.001],perioperative blood transfusion[OR=4.73,95％CI(2.99,7.48)],P＜0.001],mechanical ventilation time[MD=5.49,95％CI(3.18,7.80),P＜0.001]and hospital stay[MD=1.53,95％CI(0.98,2.08),P＜0.001]were risk factors for perioperative delirium in patients with type B aortic dissection.Conclusion:Age,age ≥60 years old,history of alcohol consumption,albumin level＜30 g/L,erythrocyte sedimentation rate,anesthesia time,operation time,perioperative blood transfusion,mechanical ventilation time and hospital stay are risk factors for perioperative delirium in patients with type B aortic dissection.Medical staff can refer to the above risk factors to formulate targeted prevention and treatment measures for perioperative delirium,with the aim of reducing the incidence of delirium in patients and improving their clinical prognosis.
Keywords：type B aortic dissectionperioperative perioddeliriumrisk factorsMeta-analysis
Publication Date：2026-01-15
Online Publishing Date：2026-01-28(First online date of this platform, not the publication date of the document)
Pages：6( 117-122 )