Chain mediating effect of nutritional risk and activity of daily living between frailty and fall risks in elderly patients with gastric cancer
ZHANG Yujiao
LEI Yi
LAN Jiangling
ZHANG Shizhen
ZHU Yin
Abstract：Objective:To explore the chain mediating effect of nutritional risk and daily living activities between frailty and fall risks in elderly patients with gastric cancer.Methods:A total of 235 elderly patients with gastric cancer were surveyed using the Frailty Phenotype(FP),Morse Falls Scale(MFS),Mini Nutritional Assessment-Short Form(MNA-SF),and Activities of Daily Living(ADL).Results:A total of 235 patients were included in this study,including 76 patients with asthenia,the incidence was 32.3%.There were statistically significant differences in age,occupation,educational background and complicated diseases among elderly gastric cancer patients with different degrees of weakness(P＜0.05).Pearson correlation analysis showed that frailty was positively correlated with fall risk,and nutritional risk was also positively correlated with activities of daily living.Both frailty and fall risks were inversely associated with nutritional risk and activities of daily living.The results of mediating effect test showed that the chain mediating effect between nutritional risk and activity of daily living was established,and the total indirect effect was 52.1%.Conclusions:Nutritional risk and activity of daily living have a chain mediating effect between frailty and fall risk,and the occurrence of frailty can be slowed down by improving nutritional status,activity of daily living and fall risk,which provides reference for predicting the occurrence of frailty.
Keywords：elderlygastric cancerfrailtyfall risknutritional riskactivities of daily livingchain mediation
Publication Date：2025-02-14
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 397-401 )